Neutrophil Production and Function in Newborn Infants

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Neutrophil Chemotaxis and Respiratory Burst in Term and Preterm Newborn Infants

Stålhammar, M. 2016. Neutrophil Chemotaxis and Respiratory Burst in Term and Preterm Newborn Infants. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1265. 47 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9722-4. Neutrophil activation is the most important initial immune defense against invading microbes in newborn infants. The reduced neutro...

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Lung function by tidal breathing in awake healthy newborn infants.

The increasing availability of appliances for measuring lung function in infants may allow clinical and epidemiological applications. The aim of the present study was to establish reference values for tidal breathing lung function in awake newborn infants and to investigate potential sources of variability. Tidal flow-volume loops were measured in 803 awake, healthy infants (427 males and 376 f...

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Defective neutrophil function in low-birth-weight, premature infants.

A whole-blood technique was used to measure simultaneously neutrophil migration, uptake, and killing of candida in 27 premature infants of low birth weight (less than 1500 g). Neutrophil migration was consistently reduced, especially in the first two weeks of life. Phagocytosis was also reduced, particularly in the first week of life and in sick patients. Killing was usually normal, except in s...

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Differential neutrophil chemotactic response towards IL-8 and bacterial N-formyl peptides in term newborn infants

BACKGROUND A prerequisite for an effective innate immunity is the migrative ability of neutrophils to respond to inflammatory and infectious agents such as the intermediate interleukin (IL)-8 and the end-target formyl-methionyl-leucyl-phenylalanine (fMLP) chemoattractants. The aim was to study the chemotactic capacity of neutrophils from newborn infants and adults in response to IL-8 and the ba...

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ژورنال

عنوان ژورنال: British Journal of Haematology

سال: 2000

ISSN: 0007-1048

DOI: 10.1046/j.1365-2141.2000.01992.x